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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPTE
All Species:
0.91
Human Site:
Y473
Identified Species:
2
UniProt:
P56180
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56180
NP_954868.1
551
64306
Y473
V
F
D
G
P
P
L
Y
D
D
V
K
V
Q
F
Chimpanzee
Pan troglodytes
XP_509584
486
53797
V412
T
A
S
I
L
I
N
V
Y
D
S
P
S
L
Y
Rhesus Macaque
Macaca mulatta
XP_001082960
622
70709
E510
F
Y
R
N
P
I
K
E
I
L
K
T
A
R
K
Dog
Lupus familis
XP_848413
692
79416
P618
I
Q
L
S
N
C
P
P
L
Y
D
D
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_954866
664
76687
V590
T
D
R
A
I
I
N
V
F
H
C
P
A
L
Y
Rat
Rattus norvegicus
NP_001102347
673
77862
F594
D
K
V
I
I
N
V
F
N
C
P
A
L
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513133
495
57137
P421
I
I
G
L
E
G
C
P
V
L
C
G
D
V
K
Chicken
Gallus gallus
XP_417079
511
58892
E437
D
S
V
V
I
G
L
E
D
S
P
V
I
S
G
Frog
Xenopus laevis
NP_001090072
509
58511
S434
G
N
N
S
I
V
L
S
L
E
G
F
P
V
I
Zebra Danio
Brachydanio rerio
NP_001020629
511
58583
Q437
N
A
V
V
I
S
L
Q
D
G
P
I
V
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788391
351
40843
G277
P
H
C
P
V
L
H
G
D
V
K
I
R
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
20.1
49.4
N.A.
50.1
50
N.A.
48.4
49.5
49.3
47.1
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
38.8
35.3
61.4
N.A.
63.4
63.4
N.A.
63.3
65.3
65.1
63.8
N.A.
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
6.6
6.6
6.6
N.A.
0
0
N.A.
0
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
20
20
N.A.
6.6
26.6
N.A.
6.6
20
20
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
10
0
0
0
0
0
0
0
10
19
0
0
% A
% Cys:
0
0
10
0
0
10
10
0
0
10
19
0
0
0
0
% C
% Asp:
19
10
10
0
0
0
0
0
37
19
10
10
10
0
10
% D
% Glu:
0
0
0
0
10
0
0
19
0
10
0
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
10
10
0
0
10
0
10
10
% F
% Gly:
10
0
10
10
0
19
0
10
0
10
10
10
0
0
19
% G
% His:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
19
10
0
19
46
28
0
0
10
0
0
19
10
0
10
% I
% Lys:
0
10
0
0
0
0
10
0
0
0
19
10
0
10
28
% K
% Leu:
0
0
10
10
10
10
37
0
19
19
0
0
10
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
10
10
10
10
19
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
19
10
10
19
0
0
28
19
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
19
0
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
10
10
19
0
10
0
10
0
10
10
0
10
10
0
% S
% Thr:
19
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% T
% Val:
10
0
28
19
10
10
10
19
10
10
10
10
28
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
10
10
10
0
0
0
10
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _